Imdur (Isosorbide Mononitrate) Tablets: Uses, Dosage, Safety and Interactions

Imdur is a prescription nitrate medicine containing isosorbide mononitrate. It relaxes blood vessels and is used to help prevent angina pectoris caused by coronary artery disease. By reducing the workload on the heart and improving the balance between oxygen supply and demand, it can reduce the frequency of angina episodes in appropriately selected patients. Imdur is not intended to stop chest pain that has already started.

Any new, severe, prolonged, or changing chest pain needs urgent assessment because it may be a heart attack or another emergency. Do not assume that all chest discomfort is routine angina. A clinician should establish a diagnosis, explain the emergency plan, and advise whether a fast-acting nitrate or another rescue treatment is needed. Imdur should be used as part of a cardiovascular care plan that may also include risk-factor management and other prescribed medicines.

Patients with a valid prescription may buy Imdur from a regulated pharmacy. The Imdur price can differ by strength, extended-release formulation, quantity, manufacturer, pharmacy, and insurance arrangements. Cost should never lead to missed doses, a change from extended-release to immediate-release tablets, or use of an unverified source.

Indications

Imdur extended-release tablets are used for prevention of angina due to coronary artery disease. They are not used to treat an acute angina attack because the onset is not sufficiently rapid for rescue. If chest pain occurs at rest, is more intense than usual, lasts more than a few minutes, or comes with breathlessness, sweating, nausea, fainting, or pain spreading to the arm, jaw, back, or shoulder, seek emergency care immediately.

Angina treatment should be reviewed regularly. The prescriber may monitor blood pressure, heart rate, symptom frequency, exercise tolerance, and use of any rescue medication. Tell the care team if angina becomes more frequent, occurs with less exertion, wakes you from sleep, or does not respond as expected to the emergency plan. These changes can signal unstable disease and should not be managed by increasing Imdur independently.

Dosage

Take Imdur exactly as prescribed, generally once daily for the extended-release formulation. Swallow extended-release tablets whole unless the pharmacist confirms that your specific product may be split; do not crush or chew them. The regimen is designed to provide a daily low-nitrate interval to help limit nitrate tolerance. Changing the timing or taking additional tablets can reduce effectiveness and cause a dangerous fall in blood pressure.

Available extended-release strengths commonly include 30 mg, 60 mg, and 120 mg. Patients with a valid prescription may buy Imdur 30 mg when that strength matches the prescribed regimen. Patients with a valid prescription may buy Imdur 60 mg only as directed on the dispensing label. Patients with a valid prescription may buy Imdur 120 mg when it is the clinician-selected strength. The Imdur price of a different strength does not make it an appropriate substitute.

If a dose is missed, take it when remembered unless the next scheduled dose is near; in that case, skip the missed dose. Do not double doses. Do not stop Imdur abruptly without speaking to the prescriber, since angina may worsen. Keep tablets in their original container, protected from moisture and out of reach of children and pets.

Safety Information

Do not take Imdur if you have had a serious allergic reaction to isosorbide mononitrate, isosorbide dinitrate, nitroglycerin, or another nitrate. It can cause headache, dizziness, flushing, weakness, palpitations, nausea, and low blood pressure, especially when treatment begins or the dose is increased. Rise slowly from sitting or lying positions. Avoid driving, operating machinery, or hazardous work until you know how it affects you.

Tell the prescriber about low blood pressure, dehydration, recent heart attack, heart failure, valve disease, hypertrophic cardiomyopathy, anemia, kidney or liver disease, glaucoma, alcohol use, pregnancy, and breastfeeding. Alcohol and other medicines that lower blood pressure can add to dizziness or fainting. Severe headache is common with nitrates, but a sudden, unusually severe headache or headache with weakness, speech difficulty, confusion, or vision loss requires urgent evaluation.

Call emergency services for fainting, severe dizziness, collapse, trouble breathing, blue or gray lips, seizures, or suspected overdose. Do not attempt to manage overdose symptoms at home. Patients receiving Imdur with a valid prescription should keep it secured and never share it with another person, including someone who has chest pain.

Interactions

Imdur must never be combined with phosphodiesterase-5 inhibitors used for erectile dysfunction or pulmonary hypertension, including sildenafil, tadalafil, vardenafil, avanafil, or similar products. The combination can cause profound, potentially life-threatening low blood pressure, fainting, heart attack, or stroke. Tell emergency clinicians when the last nitrate or PDE-5 inhibitor dose was taken.

Other blood-pressure medicines, calcium-channel blockers, alpha blockers, alcohol, and certain psychiatric medicines can increase hypotension risk. The full medicine list should include prescription drugs, over-the-counter products, herbal supplements, and recreational substances. The Imdur price does not establish safety or equivalence; a pharmacist should review interactions before any treatment is added or changed.

Medical disclaimer: This content is informational and does not replace advice, diagnosis, or treatment from a licensed healthcare professional. Imdur is a prescription medicine, and patients should follow their prescriber’s directions and seek professional advice for questions about their treatment.